Dr Mark Humphries (Research Associate)

Contact
- Department of Psychology, University of Sheffield, Sheffield, S10 2TP, UK.
- Tel: +44 (0) 114 222 6591
- Fax: +44 (0) 114 276 6515 (shared with department)
- Email: m.d.humphries/at/sheffield.ac.uk
Research Interests
- ICEA project
- Structure and function of the brainstem reticular formation
- The basal ganglia as an action selection mechanism
- Graph theory applications in neuroscience
- Single neuron models
- Spike train analysis techniques
- Neural substrate of decision making
- The function of the thalamic reticular nucleus
- Thalamocortical loop processing
Forthcoming work
- Ben Mitchinson, Tak-Shing Chan, Jon Chambers, Martin Pearson, Mark Humphries, Charles Fox, Kevin Gurney, Tony J. Prescott (2009), BRAHMS: Novel middleware for integrated systems computation, Advanced Engineering Informatics, in press.
Peer-reviewed print articles
2009
- Lowe, R., Humphries, M. & Ziemke, T. (2009), The dual-route hypothesis: Evaluating a neurocomputational model of fear conditioning in rats, Connection Science, 21: 15-37.
- Fox, C., Humphries, M., Mitchinson, B., Kiss, T,; Somogyvari, Z. & Prescott, T. (2009), Technical integration of hippocampus, basal ganglia and physical models for spatial navigation , Frontiers in Neuroinformatics, 3:6.
2008
2007
- Humphries, M. D., Gurney, K. & Prescott, T. J. (2007), Is there a brainstem substrate for action selection?, Philosophical Transactions of the Royal Society B: Biological Sciences, 362(1485):1627-1639.
- Humphries, M. D., & Gurney, K. (2007), A means to an end: validating models by fitting experimental data, Neurocomputing, 70:1892-1896. [Code]
- Prescott, T . J. & Humphries, M. D. (2007), Who dominates who in the dark basements of the brain? Commentary on Merker, B. “Consciousness without a cerebral cortex: A challenge for neuroscience and medicine”, Behavioral and Brain Sciences, 30:104-105.
- Humphries, M. D. & Gurney, K. (2007), Solutions methods for simple model neurons, Neural Computation, 19:3216-3225. [Code]
2006
- Humphries, M. D., Gurney, K. & Prescott, T. J. (2006), The brainstem reticular formation is a small-world, not scale-free, network, Proceedings of the Royal Society B: Biological Sciences, 273:503-511.
- Humphries, M. D., Stewart, R. D. & Gurney, K. (2006), A physiologically plausible model of action selection and oscillatory activity in the basal ganglia, Journal of Neuroscience, 26(50):12921-42. [Code]
- Humphries, M. D. & Prescott, T. J. (2006), Distributed action selection by a brainstem neural substrate: An embodied evaluation, From Animals to Animats 9: Proceedings of the Ninth International Conference on Simulation of Adaptive Behaviour, pp. 199-210, Springer-Verlag: Berlin.
- Prescott, T. J., Montes-Gonzalez, F., Gurney, K., Humphries, M. D. and Redgrave, P. (2006), A robot model of the basal ganglia: Behavior and intrinsic processing, Neural Networks, 19:31-61.
2005
- Humphries, M., Gurney, K. & Prescott, T. (2005), Action selection in a macroscopic model of the brainstem reticular formation, Modelling Natural Action Selection, J. J. Bryson, T. J. Prescott & A. Seth, pp. 61-68, AISB Press.
- Chambers, J. M., Gurney, K., Humphries, M. & Prescott, T. (2005), Mechanisms of choice in the primate brain: a quick look at positive feedback, Modelling Natural Action Selection, J. J. Bryson, T. J. Prescott & A. Seth, pp. 45-52, AISB Press..
- Humphries, M. D., Gurney, K. & Prescott, T. J. (2005), Is there an integrative center in the vertebrate brain-stem? A robotic evaluation of a model of the reticular formation viewed as an action selection device, Adaptive Behaviour, 13:97-113.
2004
- Gurney, K., Humphries, M., Wood, R., Prescott, T.J. & Redgrave, P. (2004), Testing computational hypotheses of brain systems function: a case study with the basal ganglia, Network: Computation in Neural Systems, 15:263-290. [Code]
2003
- Humphries, M. D., Prescott, T. J. & Gurney, K. N. (2003), The interaction of recurrent axon collateral networks in the basal ganglia, Artifical Neural Networks and Neural Information Processing, O. Kaynak, E. Alpaydin, E. Oja & L. Xu (Eds.), ICANN/ICONIP 2003 (LNCS 2714) pp. 797-804, Berlin: Springer-Verlag.
2002
- Prescott, T. J., Gurney, K., Montes-Gonzalez, F., Humphries, M. and Redgrave, P. (2002), The robot basal ganglia: Action selection by an embedded model of the basal ganglia, Basal Ganglia VII, L. F. B. Nicholson and R. Faulls (Eds.) New York: Plenum Press.
- Humphries, M. D. & Gurney, K. N. (2002), The role of intra-thalamic and thalamocortical circuits in action selection, Network: Computation in Neural Systems, 13:131-156. [Code]
2001
2000
- Montes Gonzalez, F. Prescott, T.J., Gurney, K. Humphries, M., & Redgrave, P. (2000), An embodied model of action selection mechanisms in the vertebrate brain, From Animals to Animats 6: Proceedings of the Sixth International Conference on Simulation of Adaptive Behaviour, J-A. Meyer, A. Berthoz, D. Floreano, H. Roitblat, & S. W. Wilson (Eds.), Cambridge MA: MIT Press.
Other work
- Humphries, M. D. (2007), High level modeling of tonic dopamine mechanisms in striatal neurons, q-bio.NC/0701022.
- Prescott, T. J. Gurney, K. Gonzalez, F. M., Humphries, M. & Redgrave, P. (2003), Action selection in a robot model of the basal ganglia: The role of simulated dopamine, Society for Neuroscience, Program No. 915.5.
- Humphries, M. D. (2002), The basal ganglia and action selection: A computational study at multiple levels of description, PhD Thesis, University of Sheffield.
- Humphries, M. D. & Gurney, K. (2000), A computational model of action selection in the basal ganglia: Thalamic and cortical interactions, European Journal of Neuroscience, 12, supp. 11, 260.10.
- Humphries, M. D. & Gurney, K. (1999), A computational model of action selection in the basal ganglia: Thalamic and cortical interactions, Technical Report AIVRU132, The University of Sheffield.